Dimethylformamide (DMF) 99.5 +%, pure

What is Dimethylformamide?

Dimethylformamide (DMF), more specifically N, N-dimethylformamide, is an amide of formic acid. DMF is used as a polar aprotic organic solvent.

Its use as a solvent for polyacrylonitrile, allowing it to be used as a synthetic fiber (Orlon, Dralon et al.), Was discovered in 1941 by Herbert Rein at IG Farben and independently at DuPont in the US in 1944.

-Chemical properties

The amide breaks down into dimethylamine and carbon monoxide when exposed to light and heat. Solutions in water are resistant to hydrolysis. Additions of acids or bases catalyze the decomposition to formic acid and dimethylamine. As a solvent, the compound is not inert for a number of substances. Violent reactions occur with substances such as sodium hydride, sodium tetrahydroborate, lithium azide, sodium, thionyl chloride and triethyl aluminum. It also reacts with halogenated hydrocarbons, such as carbon tetrachloride.

- Use

DMF is used as a solvent for a wide variety of solid, liquid or gaseous materials, for polymers such as polyacrylonitrile, PVC, polyamides, polyurethanes, epoxy resins and for cellulose and its derivatives.
DMF acts as a catalyst in the production of acid chlorides from carboxylic acids and oxalyl chloride.
Since DMF is polar aprotic, it is often used as a solvent in the laboratory for reactions with polar transition states. In the case of nucleophilic substitutions, e.g. B. drastic increases in the rate of methanol are recorded.
In chemical engineering, DMF is used as an extraction agent to separate benzene, ethyne and 1,3-butadiene.
DMF is an additive for kerosene, it serves as a catalyst for its combustion
DMF is an intermediate in the synthesis of acetals, aldehydes, carboxylic acid esters and nitriles
The Vilsmeier-Haack reagent, used for aromatics formylation and carboxylic acid chlorination, can be produced from DMF and phosphorus oxychloride.
DMF is used as a reagent for the synthesis of aldehydes via Bouveault aldehyde synthesis.
DMF-d7 is used as a solvent in NMR spectroscopy.

Technical properties

DMF, DMFA, Formic acid dimethylamide
Empirical formula C3H7NO
Molar mass (M) 73.10 g / mol
Density (D) 0.95 g / cm³
Boiling point (bp) 153 ° C
Flash point (flp) 57.5 ° C
Melting point (mp) -61 ° C
ADR 3 III
WGK 2
CAS No. [68-12-2]
EC no. 200-679-5
UN No. 2265

Downloads

$$$$$

Hazard statements
H226 Flammable liquid and vapor
H312 + H332 Harmful in contact with skin and by inhalation
H319 Causes serious eye irritation
H360D May damage the unborn child

Safety recommendations
Precautions - prevention
P280 Wear protective gloves / protective clothing / eye protection / face protection.

Precautions - response
P302 + P352 IF ON SKIN: Wash with plenty of soap and water.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for a long period of time
amount of minutes; remove contact lenses, if possible; keep rinsing.
P308 + P313 NA (possible) exposure: Get medical attention.