Ethyl oleate, Ph. Eur, USP, Extra pure

This Ethyl Oleate is of Pharmaceutical Grade (Ph. Eur / USP)

What is Ethyl Oleate?

Ethyl oleate is a chemical compound from the group of fatty acid esters.

Ethyl oleate can be obtained by direct esterification of oleic acid with ethyl alcohol in the presence of hydrogen chloride, Twitchell's reagent or chlorosulfonic acid.

Ethyl oleate is a non-flammable, viscous, colorless to yellowish liquid that is practically insoluble in water. Ethyl oleate has been identified as a soil pheromone in honey bees.

What is Ethyl Oleate used for?

-Additive

Ethyl oleate is used by compounding pharmacies as a vehicle for intramuscular drug delivery, in some cases to prepare daily doses of progesterone to support pregnancy. Studies documenting the safe use of ethyl oleate during pregnancy for both the mother and fetus have never been performed. It is regulated as a food additive in the US by the Food and Drug Administration. Ethyl oleate is used as a solvent for pharmaceutical drug preparations containing lipophilic substances such as steroids. It is also used as a lubricant and plasticizer. Louis Bouveault used ethyl oleate to demonstrate Bouveault-Blanc reduction, producing oleyl alcohol and ethanol, a method subsequently refined and published in Organic Syntheses.

-Medical aspects

Ethyl oleate is produced by the body during ethanol intoxication. It is one of the fatty acid ethyl esters (FAEE) produced after ingestion of ethanol. Some research literature implicates FAEEs such as ethyl oleate as the toxic mediators of ethanol in the body (pancreas, liver, heart and brain). Ethyl oleate may be the toxic mediator of alcohol in fetal alcohol syndrome. The oral intake of ethyl oleate has been carefully studied and due to its rapid breakdown in the digestive tract, it appears safe for oral intake.

-Other applications

Ethyl oleate is used to prepare the oily phase of the self-microemulsifying drug delivery system (SMEDDS) for tacrolimus (Tac). The compound is also used as a flavoring agent.

Buy ethyl oleate?

You can buy the best Ethyl oleate at Laboratoriumdiscounter. Our Ethyl oleate is of pharmaceutical quality and high purity, so you are guaranteed the best quality. And that for a friendly price! Delivered quickly and available in different packaging! Order your Ethyl oleate quickly at Laboratoriumdiscounter.nl. Always with volume discount!

.-Technical data

Ethyl oleate, Oleic acid ethyl ester
Empirical formula C22H38O2
Molar mass (M) 310.52 g/mol
Density (D) 0.87 g/cm³
Boiling point (bp) 168°C
Melting point (mp) -32°C
CAS no. [111-62-6]

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